Central pontine myelinolysis (CPM) is a neurological condition that happens in the pons area of your brain. In CPM, a rapid increase of sodium to correct low sodium levels (hyponatremia) damages nerve cells. Alcohol use disorder, liver transplantation and other conditions can cause hyponatremia. Many people with CPM fully recover.
Central pontine myelinolysis (CPM) is a component of osmotic demyelination syndrome (ODS). It is characterized by damage to regions of the brain, most commonly pontine white matter tracts, after rapid correction of metabolic disturbances such as hyponatremia.
Central pontine myelinolysis (CPM) is a neurological disorder that most frequently occurs when sodium deficiency is treated too rapidly. The part of the brain called the pons is especially sensitive and too much sodium can damage nerve fibers.
Central pontine myelinolysis (CPM) is now more commonly referred to as osmotic demyelination syndrome, which recognizes that the same phenomenon is also seen in other areas of the brain (previously known as extrapontine myelinolysis) 1 . As such the condition is described in the osmotic demyelination syndrome article. References
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