Both vaccine types are designed to elicit an immune response against the spike protein that is required for SARS-CoV-2 binding, fusion, and cell entry. Consequently, vaccination induces the production of anti-S and anti-RBD binding and neutralizing antibodies in the blood, but not anti-N antibodies.
In the United States (US), SARS-CoV-2 vaccines include two messenger RNA vaccines (mRNA) BNT162b2 [ 2] and mRNA-1273 [ 3] and one adenovirus vector vaccine (Ad26.COV2.S [ 4 ]). As of November 21st, 2021, 59% of the United States and 42% of the world’s population were fully vaccinated against SARS-CoV-2 [ 1 ].
SARS-CoV-2 vaccines in development Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late 2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. To mitigate the effects of the virus on public health, the economy and society, a vaccine is urgently needed.
The mRNA-1273 vaccine showed 94.1% efficacy at preventing Covid-19 illness, including severe disease. Aside from transient local and systemic reactions, no safety concerns were identified. (Funded by the Biomedical Advanced Research and Development Authority and the National Institute of Allergy and …
In the United States (US), SARS-CoV-2 vaccines include two messenger RNA vaccines (mRNA) BNT162b2 and mRNA-1273 and one adenovirus vector vaccine (Ad26.COV2.S ). As of November 21st, 2021, 59% of the United States and 42% of the world’s population were fully vaccinated against SARS-CoV-2 [ 1 ].
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