Two-dose ivermectin prophylaxis at a dose of 300 μg/kg with a gap of 72 hours was associated with a 73% reduction of SARS-CoV-2 infection among healthcare workers for the following month. Chemoprophylaxis has relevance in the containment of pandemic.
In India, especially in the province of Uttar Pradesh, Ivermectin, alongside other prophylactics, has been used successfully to treat COVID-19 patients and was responsible for remarkable drops in disease severity in the regions it was used. Yet in Canada, it is seen (and mocked) as “ horse dewormer .”. Those who try to discuss it as an.
Ivermectin, used in Delhi beginning April 20, obliterated their COVID crisis. Cases dropped by 97% over 6 weeks. The fatal mistake would have been to NOT use Ivermectin. They used it and it saved Delhi. But tragically, Tamil Nadu did not, and their state was devastated. Their new cases rose from 10,986 to 36,184 – a tripling.
Clinical symptoms of fever, cough, and sore throat were comparable among the three groups. Virological clearance was earlier in the 5-day ivermectin treatment arm when compared to the placebo group (9.7 days vs 12.7 days; p = 0.02), but this was not the case for the ivermectin + doxycycline arm (11.5 days; p = 0.27).
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