A COVID booster shot is an additional dose or doses of a vaccine given after the protection provided by the original shot(s) has begun to decrease over time. The booster helps people maintain strong protection from severe coronavirus disease.
A booster dose is an extra administration of a vaccine after an earlier ( primer) dose. After initial immunization, a booster provides a re-exposure to the immunizing antigen. It is intended to increase immunity against that antigen back to protective levels after memory against that antigen has declined through time.
Booster doses will help provide continued protection against severe disease. Booster doses were previously recommended only for populations at high risk for severe COVID-19, but the recommendation expanded in late 2021 and early 2022 to include everyone 12 years and older to help increase protection against COVID-19 illness.
A single booster dose is recommended for people age 12 and older after getting two doses of an mRNA COVID-19 vaccine or one dose of a Janssen/Johnson & Johnson COVID-19 vaccine. If you are age 12 or older, have been given both doses of the Pfizer-BioNTech COVID-19 vaccine and it’s been at least five months, you should get a single booster dose.
Medical Definition of booster dose. : a supplementary dose of a therapeutic agent designed to increase the effectiveness of one or more previously administered doses When possible, the drug [prednisone] was administered every other day, with booster doses during hemolytic crises. — Russell E. Ware et al.,
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